Efforts to control the errant products of a targeted in vivo generator.
Jaggi JS, Kappel BJ, McDevitt MR, Sgouros G, Flombaum CD, Cabassa C, Scheinberg DA.
Cancer Res. 2005 Jun 1;65(11):4888-95.
PMID: 15930310
Publications
Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death.
Seidl C, Schrock H, Seidenschwang S, Beck R, Schmid E, Abend M, Becker KF, Apostolidis C, Nikula TK, Kremmer E, Schwaiger M, Senekowitsch-Schmidtke R. Links
Eur J Nucl Med Mol Imaging. 2005 Mar;32(3):274-85. Epub 2004 Oct 2.
Treatment of neuroblastoma meningeal carcinomatosis with intrathecal application of alpha-emitting atomic nanogenerators targeting disialo-ganglioside GD2.
Miederer M, McDevitt MR, Borchardt P, Bergman I, Kramer K, Cheung NK, Scheinberg DA.
Clin Cancer Res. 2004 Oct 15;10(20):6985-92.
PMID: 15501978
Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression.
Ballangrud AM, Yang WH, Palm S, Enmon R, Borchardt PE, Pellegrini VA, McDevitt MR, Scheinberg DA, Sgouros G.
Clin Cancer Res. 2004 Jul 1;10(13):4489-97.
PMID: 1524054
Pharmacokinetics, dosimetry, and toxicity of the targetable atomic generator, 225Ac-HuM195, in nonhuman primates.
Miederer M, McDevitt MR, Sgouros G, Kramer K, Cheung NK, Scheinberg DA.
J Nucl Med. 2004 Jan;45(1):129-37.
PMID: 14734685
Targeted actinium-225 in vivo generators for therapy of ovarian cancer.
Borchardt PE, Yuan RR, Miederer M, McDevitt MR, Scheinberg DA.
Cancer Res. 2003 Aug 15;63(16):5084-90.
PMID: 12941838
Myeloablative conditioning regimens for AML allografts: 30 years later.
Gupta V, Lazarus HM, Keating A.
Bone Marrow Transplant. 2003 Nov;32(10):969-78
PMID: 14595384
Comparison of anti-CD20 and anti-CD45 antibodies for conventional and pretargeted radioimmunotherapy of B-cell lymphomas.
Pagel JM, Hedin N, Subbiah K, Meyer D, Mallet R, Axworthy D, Theodore LJ, Wilbur DS, Matthews DC, Press OW.
Blood. 2003 Mar 15;101(6):2340-8. Epub 2002 Nov 21.
PMID: 12446461
Design and synthesis of 225Ac radioimmunopharmaceuticals.
McDevitt MR, Ma D, Simon J, Frank RK, Scheinberg DA.
Appl Radiat Isot. 2002 Dec;57(6):841-7.
PMID: 12406626
Targeted alpha particle immunotherapy for myeloid leukemia.
Jurcic JG, Larson SM, Sgouros G, McDevitt MR, Finn RD, Divgi CR, Ballangrud AM, Hamacher KA, Ma D, Humm JL, Brechbiel MW, Molinet R, Scheinberg DA.
Blood. 2002 Aug 15;100(4):1233-9.
PMID: 12149203